Epac Polyclonal Antibody

产品详情

产品名称

Epac Polyclonal Antibody

产品货号

YM-A18123

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,ELISA

分子量

100kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human RAPGEF3. AA range:712-761

特异性

Epac Polyclonal Antibody detects endogenous levels of Epac protein.

基因名称

RAPGEF3

蛋白名称

Rap guanine nucleotide exchange factor 3

别名

RAPGEF3;CGEF1;EPAC;EPAC1;Rap guanine nucleotide exchange factor 3;Exchange factor directly activated by cAMP 1;Exchange protein directly activated by cAMP 1;EPAC 1;Rap1 guanine-nucleotide-exchange factor directly activated by cAMP;

基因ID-1

10411

SwissProt

O95398

背景

caution:It is uncertain whether Met-1 or Met-43 is the initiator.,domain:The DEP domain is involved in membrane localization independent from regulation by cAMP.,function:Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP.,similarity:Contains 1 cyclic nucleotide-binding domain.,similarity:Contains 1 DEP domain.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 Ras-GEF domain.,tissue specificity:Widely expressed with highest levels in adult kidney, heart, thyroid and brain, and fetal kidney.,

细胞定位

Endomembrane system .