Ephrin-B3 Polyclonal Antibody

产品详情

产品名称

Ephrin-B3 Polyclonal Antibody

产品货号

YM-A18148

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

36kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human EFNB3. AA range:221-270

特异性

Ephrin-B3 Polyclonal Antibody detects endogenous levels of Ephrin-B3 protein.

基因名称

EFNB3

蛋白名称

Ephrin-B3

别名

EFNB3;EPLG8;LERK8;Ephrin-B3;EPH-related receptor transmembrane ligand ELK-L3;EPH-related receptor tyrosine kinase ligand 8;LERK-8

基因ID-1

1949

SwissProt

Q15768

背景

EFNB3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. Moreover, since levels of EFNB3 expression were particularly high in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH Receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the

细胞定位

Membrane; Single-pass type I membrane protein.