FGFR-5 Polyclonal Antibody

产品详情

产品名称

FGFR-5 Polyclonal Antibody

产品货号

YM-A18228

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

54kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from FGFR-5 . at AA range: 130-210

特异性

FGFR-5 Polyclonal Antibody detects endogenous levels of FGFR-5 protein.

基因名称

FGFRL1

蛋白名称

Fibroblast growth factor receptor-like 1

别名

FGFRL1;FGFR5;FHFR;Fibroblast growth factor receptor-like 1;FGF receptor-like protein 1;FGF homologous factor receptor;FGFR-like protein;Fibroblast growth factor receptor 5;FGFR-5

基因ID-1

53834

SwissProt

Q8N441

背景

The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other

细胞定位

Membrane ; Single-pass type I membrane protein . Predominantly localized in the plasma membrane but also detected in the Golgi and in secretory vesicles.