FoxC1/2 Polyclonal Antibody

产品详情

产品名称

FoxC1/2 Polyclonal Antibody

产品货号

YM-A18260

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

57kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human FOXC1/2. AA range:151-200

特异性

FoxC1/2 Polyclonal Antibody detects endogenous levels of FoxC1/2 protein.

基因名称

FOXC1/FOXC2

蛋白名称

Forkhead box protein C1/2

别名

FOXC1;FKHL7;FREAC3;Forkhead box protein C1;Forkhead-related protein FKHL7;Forkhead-related transcription factor 3;FREAC-3;FOXC2;FKHL14;MFH1;Forkhead box protein C2;Forkhead-related protein FKHL14;Mesenchyme fork head protein 1;

基因ID-1

2296;2303

SwissProt

Q12948;Q99958

背景

This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly. [provided by RefSeq, Jul 2008],

细胞定位

Nucleus . Colocalizes with PITX2 isoform 3 in the nucleus at subnuclear chromatine regions (PubMed:16449236). Colocalizes with CBX5 to a heterochromatin-rich region of the nucleus (PubMed:15684392). Colocalizes with GLI2 in the nucleus (By similarity). .