FucT-III Polyclonal Antibody

产品详情

产品名称

FucT-III Polyclonal Antibody

产品货号

YM-A18306

规格

50μL;100μL

种属反应

Human

实验应用

WB,IHC,IF,ELISA

分子量

42kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human FUT3. AA range:91-140

特异性

FucT-III Polyclonal Antibody detects endogenous levels of FucT-III protein.

基因名称

FUT3

蛋白名称

Galactoside 3(4)-L-fucosyltransferase

别名

FUT3;FT3B;LE;Galactoside 3;4;-L-fucosyltransferase;Blood group Lewis alpha-4-fucosyltransferase;Lewis FT;Fucosyltransferase 3;Fucosyltransferase III;FucT-III

基因ID-1

2525

SwissProt

P21217

背景

The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008],

细胞定位

Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein . Membrane-bound form in trans cisternae of Golgi.