GCS-β-2 Polyclonal Antibody

产品详情

产品名称

GCS-β-2 Polyclonal Antibody

产品货号

YM-A18383

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

IHC,IF,ELISA

分子量

70kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human GCS-beta-2. AA range:53-102

特异性

GCS-β-2 Polyclonal Antibody detects endogenous levels of GCS-β-2 protein.

基因名称

GUCY1B2

蛋白名称

Guanylate cyclase soluble subunit beta-2

别名

GUCY1B2;Guanylate cyclase soluble subunit beta-2;GCS-beta-2

基因ID-1

2974

SwissProt

O75343

背景

Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit. The enzyme converts GTP into the second messenger cGMP and plays a major role in the cardiovascular system as a receptor for nitric oxide. Unlike other guanylyl cyclases, GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation.

细胞定位

Cytoplasm.