GPR172A Polyclonal Antibody

产品详情

产品名称

GPR172A Polyclonal Antibody

产品货号

YM-A18476

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,IF,ELISA

分子量

46kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human PEVR1. AA range:43-92

特异性

GPR172A Polyclonal Antibody detects endogenous levels of GPR172A protein.

基因名称

SLC52A2

蛋白名称

Solute carrier family 52 riboflavin transporter member 2

别名

SLC52A2;GPR172A;PAR1;RFT3;Solute carrier family 52;riboflavin transporter, member 2;Porcine endogenous retrovirus A receptor 1;PERV-A receptor 1;Protein GPR172A;Riboflavin transporter 3;hRFT3

基因ID-1

79581

SwissProt

Q9HAB3

背景

This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunctio

细胞定位

Cell membrane ; Multi-pass membrane protein .