Granzyme H Polyclonal Antibody

产品详情

产品名称

Granzyme H Polyclonal Antibody

产品货号

YM-A18525

规格

50μL;100μL

种属反应

Human

实验应用

WB,IHC,IF,ELISA

分子量

23kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human GRAH. AA range:51-100

特异性

Granzyme H Polyclonal Antibody detects endogenous levels of Granzyme H protein.

基因名称

GZMH

蛋白名称

Granzyme H

别名

GZMH;CGL2;CTSGL2;Granzyme H;CCP-X;Cathepsin G-like 2;CTSGL2;Cytotoxic T-lymphocyte proteinase;Cytotoxic serine protease C;CSP-C

基因ID-1

2999

SwissProt

P20718

背景

This gene encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14. [provided by RefSeq, Nov 2015],

细胞定位

Cytolytic granule .