GRB14 Polyclonal Antibody

产品详情

产品名称

GRB14 Polyclonal Antibody

产品货号

YM-A18530

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

61kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human GRB14. AA range:81-130

特异性

GRB14 Polyclonal Antibody detects endogenous levels of GRB14 protein.

基因名称

GRB14

蛋白名称

Growth factor receptor-bound protein 14

别名

GRB14;Growth factor receptor-bound protein 14;GRB14 adapter protein

基因ID-1

2888

SwissProt

Q14449

背景

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],

细胞定位

Cytoplasm . Endosome membrane ; Peripheral membrane protein . Upon insulin stimulation, translocates to the plasma membrane. .