GRP1 Polyclonal Antibody

产品详情

产品名称

GRP1 Polyclonal Antibody

产品货号

YM-A18548

规格

50μL;100μL

种属反应

Human,Mouse,Rat,Monkey

实验应用

WB,ELISA

分子量

46kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human GRP1. AA range:351-400

特异性

GRP1 Polyclonal Antibody detects endogenous levels of GRP1 protein.

基因名称

CYTH3

蛋白名称

Cytohesin-3

别名

CYTH3;ARNO3;GRP1;PSCD3;Cytohesin-3;ARF nucleotide-binding site opener 3;Protein ARNO3;General receptor of phosphoinositides 1;Grp1;PH;SEC7 and coiled-coil domain-containing protein 3

基因ID-1

9265

SwissProt

O43739

背景

This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm, cytosol. Cell membrane ; Peripheral membrane protein . Cell junction, adherens junction . Cell junction, tight junction . Translocates from the cytosol to membranes enriched in phosphatidylinositol 3,4,5-trisphosphate. .