hCAP-G Polyclonal Antibody

产品详情

产品名称

hCAP-G Polyclonal Antibody

产品货号

YM-A18573

规格

50μL;100μL

种属反应

Human

实验应用

WB,ELISA

分子量

115kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human NCAPG. AA range:951-1000

特异性

hCAP-G Polyclonal Antibody detects endogenous levels of hCAP-G protein.

基因名称

NCAPG

蛋白名称

Condensin complex subunit 3

别名

NCAPG;CAPG;NYMEL3;Condensin complex subunit 3;Chromosome-associated protein G;Condensin subunit CAP-G;hCAP-G;Melanoma antigen NY-MEL-3;Non-SMC condensin I complex subunit G;XCAP-G homolog

基因ID-1

64151

SwissProt

Q9BPX3

背景

This gene encodes a subunit of the condensin complex, which is responsible for the condensation and stabilization of chromosomes during mitosis and meiosis. Phosphorylation of the encoded protein activates the condensin complex. There are pseudogenes for this gene on chromosomes 8 and 15. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],

细胞定位

Nucleus. Cytoplasm. Chromosome. In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.