Histamine H1 Receptor Polyclonal Antibody

产品详情

产品名称

Histamine H1 Receptor Polyclonal Antibody

产品货号

YM-A18608

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,IF,ELISA

分子量

60kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human HRH1. AA range:141-190

特异性

Histamine H1 Receptor Polyclonal Antibody detects endogenous levels of Histamine H1 Receptor protein.

基因名称

HRH1

蛋白名称

Histamine H1 receptor

别名

HRH1;Histamine H1 receptor;H1R;HH1R

基因ID-1

3269

SwissProt

P35367

背景

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. It has been associated with multiple processes, including memory and learning, circadian rhythm, and thermoregulation. It is also known to contribute to the pathophysiology of allergic diseases such as atopic dermatitis, asthma, anaphylaxis and allergic rhinitis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by Ref

细胞定位

Cell membrane ; Multi-pass membrane protein .