HMG-2 Polyclonal Antibody

产品详情

产品名称

HMG-2 Polyclonal Antibody

产品货号

YM-A18633

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

27kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human HMGB2. AA range:131-180

特异性

HMG-2 Polyclonal Antibody detects endogenous levels of HMG-2 protein.

基因名称

HMGB2

蛋白名称

High mobility group protein B2

别名

HMGB2;HMG2;High mobility group protein B2;High mobility group protein 2;HMG-2

基因ID-1

3148

SwissProt

P26583

背景

This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. [provided by RefSeq, Jul 2008],

细胞定位

Nucleus . Chromosome . Cytoplasm . Secreted . In basal state predominantly nuclear. .