HNF-4α/γ Polyclonal Antibody

产品详情

产品名称

HNF-4α/γ Polyclonal Antibody

产品货号

YM-A18636

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

52kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human HNF4 alpha/gamma. AA range:91-140

特异性

HNF-4α/γ Polyclonal Antibody detects endogenous levels of HNF-4α/γ protein.

基因名称

HNF4A/HNF4G

蛋白名称

Hepatocyte nuclear factor 4-alpha/gamma

别名

HNF4A;HNF4;NR2A1;TCF14;Hepatocyte nuclear factor 4-alpha;HNF-4-alpha;Nuclear receptor subfamily 2 group A member 1;Transcription factor 14;TCF-14;Transcription factor HNF-4;HNF4G;NR2A2;Hepatocyte nuclear factor 4-gamma;HNF-4-ga

基因ID-1

3172;3174

SwissProt

P41235;Q14541

背景

The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012],

细胞定位

Nucleus.