hnRNP Q Polyclonal Antibody

产品详情

产品名称

hnRNP Q Polyclonal Antibody

产品货号

YM-A18652

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

62kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human hnRNP Q. AA range:236-285

特异性

hnRNP Q Polyclonal Antibody detects endogenous levels of hnRNP Q protein.

基因名称

SYNCRIP

蛋白名称

Heterogeneous nuclear ribonucleoprotein Q

别名

SYNCRIP;HNRPQ;NSAP1;Heterogeneous nuclear ribonucleoprotein Q;hnRNP Q;Glycine- and tyrosine-rich RNA-binding protein;GRY-RBP;NS1-associated protein 1;Synaptotagmin-binding;cytoplasmic RNA-interacting protein

基因ID-1

10492

SwissProt

O60506

背景

This gene encodes a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 20. [provided by RefSeq, Dec 2011],

细胞定位

Cytoplasm . Microsome . Endoplasmic reticulum . Nucleus . The tyrosine phosphorylated form bound to RNA is found in microsomes (By similarity). Localized in cytoplasmic mRNP granules containing untranslated mRNAs (By similarity). .; [Isoform 1]: Nucleus, nucleoplasm . Expressed predominantly in the nucleoplasm. .; [Isoform 2]: Nucleus, nucleoplasm . Expressed predominantly in the nucleoplasm. .; [Isoform 3]: Nucleus, nucleoplasm . Expressed predominantly in the nucleoplasm. .