IRAK-M Polyclonal Antibody

产品详情

产品名称

IRAK-M Polyclonal Antibody

产品货号

YM-A18792

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IHC,IF,ELISA

分子量

68kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human IRAK3. AA range:491-540

特异性

IRAK-M Polyclonal Antibody detects endogenous levels of IRAK-M protein.

基因名称

IRAK3

蛋白名称

Interleukin-1 receptor-associated kinase 3

别名

IRAK3;Interleukin-1 receptor-associated kinase 3;IRAK-3;IL-1 receptor-associated kinase M;IRAK-M

基因ID-1

11213

SwissProt

Q9Y616

背景

This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010],

细胞定位

Cytoplasm . Nucleus . In dendritic cells, translocates into the nucleus upon IL33 stimulation. .