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产品详情
产品名称
IκB-β Polyclonal Antibody
产品货号
YM-A18806
规格
50μL;100μL
种属反应
Human,Mouse
实验应用
WB,IHC
分子量
37kD
宿主
Rabbit
同种型
IgG
修饰
Unmodified
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克降性
Polyclonal
克隆号
免疫原
The antiserum was produced against synthesized peptide derived from human IkappaB-beta. AA range:4-53
特异性
IκB-β Polyclonal Antibody detects endogenous levels of IκB-β protein.
基因名称
NFKBIB
蛋白名称
NF-kappa-B inhibitor beta
别名
NFKBIB;IKBB;TRIP9;NF-kappa-B inhibitor beta;NF-kappa-BIB;I-kappa-B-beta;IkB-B;IkB-beta;IkappaBbeta;Thyroid receptor-interacting protein 9;TR-interacting protein 9;TRIP-9
基因ID-1
4793
SwissProt
Q15653
背景
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011],
细胞定位
Cytoplasm . Nucleus .
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