LRRC41 Polyclonal Antibody

产品详情

产品名称

LRRC41 Polyclonal Antibody

产品货号

YM-A18952

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

80kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human LRRC41. AA range:391-440

特异性

LRRC41 Polyclonal Antibody detects endogenous levels of LRRC41 protein.

基因名称

LRRC41

蛋白名称

Leucine-rich repeat-containing protein 41

别名

LRRC41;MUF1;PP7759;Leucine-rich repeat-containing protein 41;Protein Muf1

基因ID-1

10489

SwissProt

Q15345

背景

caution:It is uncertain whether Met-1 or Met-23 is the initiator.,domain:The elongin BC complex binding domain is also known as BC-box with the consensus [APST]-L-x(3)-C-x(3)-[AILV].,function:Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Translation N-terminally extended.,similarity:Contains 7 LRR (leucine-rich) repeats.,subunit:Part of an E3 ubiquitin-protein ligase complex with Elongin BC (TCEB1 and TCEB2), RBX1 and CUL5. Component of a probable ECS(LRRC41) complex which contains CUL5, RNF7/RBX2, Elongin BC and LRRC41. Interacts with CUL5, RNF7, TCEB1 and TCEB2.,

细胞定位

nucleus,cytoplasm,membrane,