MARCH5 Polyclonal Antibody

产品详情

产品名称

MARCH5 Polyclonal Antibody

产品货号

YM-A19003

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

IF,WB,ELISA

分子量

37kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human MARCH5. AA range:21-70

特异性

MARCH5 Polyclonal Antibody detects endogenous levels of 40607 protein.

基因名称

MARCH5

蛋白名称

E3 ubiquitin-protein ligase MARCH5

别名

MARCH5;RNF153;E3 ubiquitin-protein ligase MARCH5;Membrane-associated RING finger protein 5;Membrane-associated RING-CH protein V;MARCH-V;Mitochondrial ubiquitin ligase;MITOL;RING finger protein 153

基因ID-1

54708

SwissProt

Q9NX47

背景

MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2; MIM 608507) and DRP1 (DNM1L; MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM, Mar 2008],

细胞定位

Mitochondrion outer membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Authors show that the protein can be detected in endoplasmic reticulum (PubMed:14722266). Authors (PubMed:16874301) show its presence only in mitochondria (PubMed:16874301). .