MARK4 Polyclonal Antibody

产品详情

产品名称

MARK4 Polyclonal Antibody

产品货号

YM-A19007

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

IF,ELISA

分子量

83kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications;

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human MARK4. AA range:461-510

特异性

MARK4 Polyclonal Antibody detects endogenous levels of MARK4 protein.

基因名称

MARK4

蛋白名称

MAP/microtubule affinity-regulating kinase 4

别名

MARK4;KIAA1860;MARKL1;MAP/microtubule affinity-regulating kinase 4;MAP/microtubule affinity-regulating kinase-like 1

基因ID-1

57787

SwissProt

Q96L34

背景

microtubule affinity regulating kinase 4(MARK4) Homo sapiens This gene encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],

细胞定位

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, cilium axoneme . Cytoplasm . Cell projection, dendrite . Localized at the tips of neurite-like processes in differentiated neuroblast cells. Detected in the cytoplasm and neuropil of the hippocampus. .