Matriptase Polyclonal Antibody

产品详情

产品名称

Matriptase Polyclonal Antibody

产品货号

YM-A19018

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IF,ELISA

分子量

95kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human ST14. AA range:10-59

特异性

Matriptase Polyclonal Antibody detects endogenous levels of Matriptase protein.

基因名称

ST14

蛋白名称

Suppressor of tumorigenicity 14 protein

别名

ST14;PRSS14;SNC19;TADG15;Suppressor of tumorigenicity 14 protein;Matriptase;Membrane-type serine protease 1;MT-SP1;Prostamin;Serine protease 14;Serine protease TADG-15;Tumor-associated differentially-expressed gene 15 protein

基因ID-1

6768

SwissProt

Q9Y5Y6

背景

The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq, Jul 2008],

细胞定位

Membrane ; Single-pass type II membrane protein .