MLH1 Polyclonal Antibody

产品详情

产品名称

MLH1 Polyclonal Antibody

产品货号

YM-A19113

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC

分子量

85kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human MLH1. AA range:441-490

特异性

MLH1 Polyclonal Antibody detects endogenous levels of MLH1 protein.

基因名称

MLH1

蛋白名称

DNA mismatch repair protein Mlh1

别名

MLH1;COCA2;DNA mismatch repair protein Mlh1;MutL protein homolog 1

基因ID-1

4292

SwissProt

P40692

背景

This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009],

细胞定位

Nucleus . Chromosome . Recruited to chromatin in a MCM9-dependent manner. .