MYPT3 Polyclonal Antibody

产品详情

产品名称

MYPT3 Polyclonal Antibody

产品货号

YM-A19266

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IF,ELISA,IHC

分子量

60kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IF/ICC1:50-200;ELISA 1:2000-20000;IHC 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human PPP1R16A. AA range:362-411

特异性

MYPT3 Polyclonal Antibody detects endogenous levels of MYPT3 protein.

基因名称

PPP1R16A

蛋白名称

Protein phosphatase 1 regulatory subunit 16A

别名

PPP1R16A;MYPT3;Protein phosphatase 1 regulatory subunit 16A;Myosin phosphatase-targeting subunit 3

基因ID-1

84988

SwissProt

Q96I34

背景

Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains, which is crucial for muscle and intracellular movement. MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit, a myosin phosphatase targeting (MYPT) subunit, and another smaller subunit. The protein encoded by this gene represents an MYPT subunit, which is responsible for directing PP1c to its intended targets. However, while other MYPTs result in PP1c activation after becoming phosphorylated, the encoded protein is phosphorylated by protein kinase A and then inhibits the catalytic activity of PP1c. [provided by RefSeq, Jul 2016],

细胞定位

Cell membrane ; Lipid-anchor .