Na+ CP type VIIα Polyclonal Antibody

产品详情

产品名称

Na+ CP type VIIα Polyclonal Antibody

产品货号

YM-A19277

规格

50μL;100μL

种属反应

Human,Monkey

实验应用

WB,IHC

分子量

200kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human SCN7A. AA range:771-820

特异性

Na+ CP type VIIα Polyclonal Antibody detects endogenous levels of Na+ CP type VIIα protein.

基因名称

SCN7A

蛋白名称

Sodium channel protein type 7 subunit alpha

别名

SCN7A;SCN6A;Sodium channel protein type 7 subunit alpha;Putative voltage-gated sodium channel subunit alpha Nax;Sodium channel protein cardiac and skeletal muscle subunit alpha;Sodium channel protein type VII subunit alpha

基因ID-1

6332

SwissProt

Q01118

背景

This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011],

细胞定位

Cell membrane ; Multi-pass membrane protein .