Na+ CP-pan Polyclonal Antibody

产品详情

产品名称

Na+ CP-pan Polyclonal Antibody

产品货号

YM-A19278

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

230kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human Sodium Channel. AA range:1466-1515

特异性

Na+ CP-pan Polyclonal Antibody detects endogenous levels of Na+ CP-pan protein.

基因名称

SCN1A/SCN2A/SCN3A/SCN4A/SCN5A/SCN8A/SCN9A/SCN10A/SCN11A

蛋白名称

Sodium channel protein type 1 subunit alpha

别名

SCN1A;NAC1;SCN1;Sodium channel protein type 1 subunit alpha;Sodium channel protein brain I subunit alpha;Sodium channel protein type I subunit alpha;Voltage-gated sodium channel subunit alpha Nav1.1;SCN2A;NAC2;SCN2A1;SCN2A2;Sodiu

基因ID-1

6323;6326;6328;6329;6331;6334;6335;6336;11280

SwissProt

P35498;Q99250;Q9NY46;P35499;Q14524;Q9UQD0;Q15858;Q9Y5Y9;Q9UI33

背景

Voltage-dependent sodium channels are heteromeric complexes that regulate sodium exchange between intracellular and extracellular spaces and are essential for the generation and propagation of action potentials in muscle cells and neurons. Each sodium channel is composed of a large pore-forming, glycosylated alpha subunit and two smaller beta subunits. This gene encodes a sodium channel alpha subunit, which has four homologous domains, each of which contains six transmembrane regions. Allelic variants of this gene are associated with generalized epilepsy with febrile seizures and epileptic encephalopathy. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, th

细胞定位

Cell membrane ; Multi-pass membrane protein .