NBPF1/9/10/12/14/15/16/20 Polyclonal Antibody

产品详情

产品名称

NBPF1/9/10/12/14/15/16/20 Polyclonal Antibody

产品货号

YM-A19290

规格

50μL;100μL

种属反应

Human

实验应用

WB,IHC,IF,ELISA

分子量

36kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human NBPF1/9/10/12/14/15/16/20. AA range:121-150

特异性

NBPF1/9/10/12/14/15/16/20 Polyclonal Antibody detects endogenous levels of NBPF1/9/10/12/14/15/16/20 protein.

基因名称

NBPF12

蛋白名称

Neuroblastoma breakpoint family member 12

别名

NBPF12;COAS1;KIAA1245;Neuroblastoma breakpoint family member 12;Chromosome 1 amplified sequence 1;NBPF10;Neuroblastoma breakpoint family member 10;NBPF16;Neuroblastoma breakpoint family member 16;NBPF1;KIAA1693;Neuroblastoma brea

基因ID-1

55672;400818;284565;25832

SwissProt

Q5TAG4;Q6P3W6;Q5SXJ2;Q3BBV0;Q3BBW0;Q3BBV1;Q8N660;Q5TI25

背景

This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This

细胞定位

Cytoplasm .