NEDL2 Polyclonal Antibody

产品详情

产品名称

NEDL2 Polyclonal Antibody

产品货号

YM-A19332

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

140-150kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human HECW2. AA range:481-530

特异性

NEDL2 Polyclonal Antibody detects endogenous levels of NEDL2 protein.

基因名称

HECW2

蛋白名称

E3 ubiquitin-protein ligase HECW2

别名

HECW2;KIAA1301;NEDL2;E3 ubiquitin-protein ligase HECW2;HECT;C2 and WW domain-containing protein 2;NEDD4-like E3 ubiquitin-protein ligase 2

基因ID-1

57520

SwissProt

Q9P2P5

背景

function:E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 C2 domain.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 2 WW domains.,subunit:Interacts with TP73.,tissue specificity:Predominantly expressed in adult brain, lung and heart.,

细胞定位

Cytoplasm . Cytoplasm, cytoskeleton, spindle .