Neurofibromin Polyclonal Antibody

产品详情

产品名称

Neurofibromin Polyclonal Antibody

产品货号

YM-A19363

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC

分子量

319kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human NF1. AA range:1551-1600

特异性

Neurofibromin Polyclonal Antibody detects endogenous levels of Neurofibromin protein.

基因名称

NF1

蛋白名称

Neurofibromin

别名

NF1;Neurofibromin;Neurofibromatosis-related protein NF-1

基因ID-1

4763

SwissProt

P21359

背景

This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008],

细胞定位

Nucleus . Nucleus, nucleolus .