Neurophysin I Polyclonal Antibody

产品详情

产品名称

Neurophysin I Polyclonal Antibody

产品货号

YM-A19370

规格

50μL;100μL

种属反应

Human,Rat

实验应用

WB,IHC,IF,ELISA

分子量

19kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human Neurophysin I. AA range:40-89

特异性

Neurophysin I Polyclonal Antibody detects endogenous levels of Neurophysin I protein.

基因名称

OXT

蛋白名称

Oxytocin-neurophysin 1

别名

OXT;OT;Oxytocin-neurophysin 1;OT-NPI

基因ID-1

5020

SwissProt

P01178

背景

This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. [provided by RefSeq, Dec 2013],

细胞定位

Secreted.