NIPP1 Polyclonal Antibody

产品详情

产品名称

NIPP1 Polyclonal Antibody

产品货号

YM-A19405

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,ELISA

分子量

40kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human PPP1R8. AA range:196-245

特异性

NIPP1 Polyclonal Antibody detects endogenous levels of NIPP1 protein.

基因名称

PPP1R8

蛋白名称

Nuclear inhibitor of protein phosphatase 1

别名

PPP1R8;ARD1;NIPP1;Nuclear inhibitor of protein phosphatase 1;NIPP-1;Protein phosphatase 1 regulatory inhibitor subunit 8

基因ID-1

5511

SwissProt

Q12972

背景

This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008],

细胞定位

Nucleus. Nucleus speckle. Primarily, but not exclusively, nuclear.; [Isoform Gamma]: Cytoplasm. Found mainly in the cytoplasm.