NQO1 Polyclonal Antibody

产品详情

产品名称

NQO1 Polyclonal Antibody

产品货号

YM-A19452

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,IF,ELISA

分子量

31kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IF 1:50-200;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human NQO1. AA range:203-252

特异性

NQO1 Polyclonal Antibody detects endogenous levels of NQO1 protein.

基因名称

NQO1

蛋白名称

NAD(P)H dehydrogenase [quinone] 1

别名

NQO1;DIA4;NMOR1;NAD;P;H dehydrogenase [quinone] 1;Azoreductase;DT-diaphorase;DTD;Menadione reductase;NAD;P;H:quinone oxidoreductase 1;Phylloquinone reductase;Quinone reductase 1;QR1

基因ID-1

1728

SwissProt

P15559

背景

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm, cytosol .