p18 Polyclonal Antibody

产品详情

产品名称

p18 Polyclonal Antibody

产品货号

YM-A19748

规格

50μL;100μL

种属反应

Human,Mouse,Monkey

实验应用

WB,IHC,IF,ELISA

分子量

18kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human p18 INK. AA range:111-160

特异性

p18 Polyclonal Antibody detects endogenous levels of p18 protein.

基因名称

CDKN2C

蛋白名称

Cyclin-dependent kinase 4 inhibitor C

别名

CDKN2C;CDKN6;Cyclin-dependent kinase 4 inhibitor C;Cyclin-dependent kinase 6 inhibitor;p18-INK4c;p18-INK6

基因ID-1

1031

SwissProt

P42773

背景

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008],

细胞定位

nucleus,cytoplasm,cytosol,