PAKβ Polyclonal Antibody

产品详情

产品名称

PAKβ Polyclonal Antibody

产品货号

YM-A19790

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

72kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human PAK3. AA range:121-170

特异性

PAKβ Polyclonal Antibody detects endogenous levels of PAKβ protein.

基因名称

PAK3

蛋白名称

Serine/threonine-protein kinase PAK 3

别名

PAK3;OPHN3;Serine/threonine-protein kinase PAK 3;Beta-PAK;Oligophrenin-3;p21-activated kinase 3;PAK-3

基因ID-1

5063

SwissProt

O75914

背景

The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Apr 2016],

细胞定位

Cytoplasm .