Pepsin A Polyclonal Antibody

产品详情

产品名称

Pepsin A Polyclonal Antibody

产品货号

YM-A19852

规格

50μL;100μL

种属反应

Human

实验应用

WB,IHC,IF,ELISA

分子量

42kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human Pepsin A. AA range:258-307

特异性

Pepsin A Polyclonal Antibody detects endogenous levels of Pepsin A protein.

基因名称

PGA3/PGA4/PGA5

蛋白名称

Pepsin A

别名

Pepsin A;PGA3;PGA4;PGA5

基因ID-1

5222;643847

SwissProt

P0DJD8;P0DJD7;P0DJD9

背景

This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer. [provided by RefSeq, Jul 2015],

细胞定位

extracellular exosome,multivesicular body lumen,