PGI2 synthase Polyclonal Antibody

产品详情

产品名称

PGI2 synthase Polyclonal Antibody

产品货号

YM-A19880

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,ELISA,IHC

分子量

57kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from the C-terminal region of human PGI2 synthase.

特异性

PGI2 synthase Polyclonal Antibody detects endogenous levels of PGI2 synthase protein.

基因名称

PTGIS

蛋白名称

Prostacyclin synthase

别名

PTGIS;CYP8;CYP8A1;Prostacyclin synthase;Prostaglandin I2 synthase

基因ID-1

5740

SwissProt

Q16647

背景

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008],

细胞定位

Endoplasmic reticulum membrane ; Single-pass membrane protein .