PHKB Polyclonal Antibody

产品详情

产品名称

PHKB Polyclonal Antibody

产品货号

YM-A19891

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IHC

分子量

124kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human KPBB. AA range:661-710

特异性

PHKB Polyclonal Antibody detects endogenous levels of PHKB protein.

基因名称

PHKB

蛋白名称

Phosphorylase b kinase regulatory subunit beta

别名

PHKB;Phosphorylase b kinase regulatory subunit beta;Phosphorylase kinase subunit beta

基因ID-1

5257

SwissProt

Q93100

背景

Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency

细胞定位

Cell membrane ; Lipid-anchor ; Cytoplasmic side .