PI 3-kinase p110α Polyclonal Antibody

产品详情

产品名称

PI 3-kinase p110α Polyclonal Antibody

产品货号

YM-A19899

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

IF,WB,IHC,ELISA

分子量

110kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IF 1:50-200;WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;Not yet tested in other applications;

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human PI 3-kinase p110alpha. AA range:470-519

特异性

PI 3-kinase p110α Polyclonal Antibody detects endogenous levels of PI 3-kinase p110α protein.

基因名称

PIK3CA

蛋白名称

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

别名

PIK3CA;Phosphatidylinositol 4;5-bisphosphate 3-kinase catalytic subunit alpha isoform;PI3-kinase subunit alpha;PI3K-alpha;PI3Kalpha;PtdIns-3-kinase subunit alpha;Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit

基因ID-1

5290

SwissProt

P42336

背景

Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22. [provided by RefSeq, Apr 2016],

细胞定位

intracellular,cytosol,plasma membrane,phosphatidylinositol 3-kinase complex,phosphatidylinositol 3-kinase complex, class IA,lamellipodium,