PIG3 Polyclonal Antibody

产品详情

产品名称

PIG3 Polyclonal Antibody

产品货号

YM-A19911

规格

50μL;100μL

种属反应

Human

实验应用

WB,IHC,IF,ELISA

分子量

36kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human QORX. AA range:241-290

特异性

PIG3 Polyclonal Antibody detects endogenous levels of PIG3 protein.

基因名称

TP53I3

蛋白名称

Quinone oxidoreductase PIG3

别名

TP53I3;PIG3;Quinone oxidoreductase PIG3;Tumor protein p53-inducible protein 3;p53-induced gene 3 protein

基因ID-1

9540

SwissProt

Q53FA7

背景

The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

细胞定位

cytosol,extracellular exosome,