Plakophilin 2 Polyclonal Antibody

产品详情

产品名称

Plakophilin 2 Polyclonal Antibody

产品货号

YM-A19957

规格

50μL;100μL

种属反应

Human,Rat

实验应用

WB,ELISA,IHC

分子量

97kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human PKP2. AA range:632-681

特异性

Plakophilin 2 Polyclonal Antibody detects endogenous levels of Plakophilin 2 protein.

基因名称

PKP2

蛋白名称

Plakophilin-2

别名

PKP2;Plakophilin-2

基因ID-1

5318

SwissProt

Q99959

背景

This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13. [provided by RefSeq, Jul 2008],

细胞定位

Nucleus . Cell junction, desmosome . Nuclear and associated with desmosomes.