PNPase Polyclonal Antibody

产品详情

产品名称

PNPase Polyclonal Antibody

产品货号

YM-A19976

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IHC,IF,ELISA

分子量

85kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human PNPT1. AA range:570-619

特异性

PNPase Polyclonal Antibody detects endogenous levels of PNPase protein.

基因名称

PNPT1

蛋白名称

Polyribonucleotide nucleotidyltransferase 1 mitochondrial

别名

PNPT1;PNPASE;Polyribonucleotide nucleotidyltransferase 1;mitochondrial;3'-5' RNA exonuclease OLD35;PNPase old-35;Polynucleotide phosphorylase 1;PNPase 1;Polynucleotide phosphorylase-like protein

基因ID-1

87178

SwissProt

Q8TCS8

背景

The protein encoded by this gene belongs to the evolutionary conserved polynucleotide phosphorylase family comprised of phosphate dependent 3'-to-5' exoribonucleases implicated in RNA processing and degradation. This enzyme is predominantly localized in the mitochondrial intermembrane space and is involved in import of RNA to mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency-13 and autosomal recessive nonsyndromic deafness-70. Related pseudogenes are found on chromosomes 3 and 7. [provided by RefSeq, Dec 2012],

细胞定位

Cytoplasm . Mitochondrion matrix . Mitochondrion intermembrane space ; Peripheral membrane protein .