PTP22 Polyclonal Antibody

产品详情

产品名称

PTP22 Polyclonal Antibody

产品货号

YM-A20060

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC

分子量

91kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from the N-terminal region of human PTP22.

特异性

PTP22 Polyclonal Antibody detects endogenous levels of PTP22 protein.

基因名称

PTPN22

蛋白名称

Tyrosine-protein phosphatase non-receptor type 22

别名

PTPN22;PTPN8;Tyrosine-protein phosphatase non-receptor type 22;Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP;Lymphoid phosphatase;LyP;PEST-domain phosphatase;PEP

基因ID-1

26191

SwissProt

Q9Y2R2

背景

This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Mar 2009],

细胞定位

Cytoplasm .