Rab 3 GAP p150 Polyclonal Antibody

产品详情

产品名称

Rab 3 GAP p150 Polyclonal Antibody

产品货号

YM-A20082

规格

50μL;100μL

种属反应

Human,Mouse,Rat,Monkey

实验应用

WB,IHC,IF,ELISA

分子量

156kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human RAB3GAP2. AA range:417-466

特异性

Rab 3 GAP p150 Polyclonal Antibody detects endogenous levels of Rab 3 GAP p150 protein.

基因名称

RAB3GAP2

蛋白名称

Rab3 GTPase-activating protein non-catalytic subunit

别名

RAB3GAP2;KIAA0839;Rab3 GTPase-activating protein non-catalytic subunit;RGAP-iso;Rab3 GTPase-activating protein 150 kDa subunit;Rab3-GAP p150;Rab3-GAP150;Rab3-GAP regulatory subunit

基因ID-1

25782

SwissProt

Q9H2M9

背景

The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.[provided by RefSeq, Oct 2009],

细胞定位

Cytoplasm. In neurons, it is enriched in the synaptic soluble fraction.