Rabaptin-5α Polyclonal Antibody

产品详情

产品名称

Rabaptin-5α Polyclonal Antibody

产品货号

YM-A20102

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

IHC,IF,ELISA

分子量

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human RABEP1. AA range:549-598

特异性

Rabaptin-5α Polyclonal Antibody detects endogenous levels of Rabaptin-5α protein.

基因名称

RABEP1

蛋白名称

Rab GTPase-binding effector protein 1

别名

RABEP1;RAB5EP;RABPT5;RABPT5A;Rab GTPase-binding effector protein 1;Rabaptin-4;Rabaptin-5;Rabaptin-5alpha;Renal carcinoma antigen NY-REN-17

基因ID-1

9135

SwissProt

Q15276

背景

function:Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A.,PTM:Proteolytic cleavage by caspases in apoptotic cells causes loss of endosome fusion activity.,similarity:Belongs to the rabaptin family.,subunit:Heterodimer with RABGEF1. The heterodimer binds RAB4A and RAB5A that have been activated by GTP-binding. Binds TSC2, GGA1, GGA2, GGA3, AP1G1 and AP1G2.,

细胞定位

Cytoplasm. Early endosome. Recycling endosome. Cytoplasmic vesicle.