Rad51B Polyclonal Antibody

产品详情

产品名称

Rad51B Polyclonal Antibody

产品货号

YM-A20118

规格

50μL;100μL

种属反应

Human,Mouse,Monkey

实验应用

WB,IHC,IF,ELISA

分子量

45kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human RAD51L1. AA range:201-250

特异性

Rad51B Polyclonal Antibody detects endogenous levels of Rad51B protein.

基因名称

RAD51B

蛋白名称

DNA repair protein RAD51 homolog 2

别名

RAD51B;RAD51L1;REC2;DNA repair protein RAD51 homolog 2;R51H2;RAD51 homolog B;Rad51B;RAD51-like protein 1

基因ID-1

5890

SwissProt

O15315

背景

RAD51 paralog B(RAD51B) Homo sapiens The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Mar 2016],

细胞定位

Nucleus .