Rec8 Polyclonal Antibody

产品详情

产品名称

Rec8 Polyclonal Antibody

产品货号

YM-A20165

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,ELISA,IHC

分子量

62kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human REC8. AA range:154-203

特异性

Rec8 Polyclonal Antibody detects endogenous levels of Rec8 protein.

基因名称

REC8

蛋白名称

Meiotic recombination protein REC8 homolog

别名

REC8;REC8L1;Meiotic recombination protein REC8 homolog;Cohesin Rec8p

基因ID-1

9985

SwissProt

O95072

背景

This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008],

细胞定位

Nucleus . Chromosome . Chromosome, centromere . In meiotic chromosomes, localized along axial elements in prophase from the leptotene to diplotene stages. At later prophase stages, diakinesis and metaphase I, localized along interstitial axes of chromosomes including both centromere and arm regions. No longer detected in arm regions in anaphase I but persists on centromere regions until metaphase II. Localized to centromeres and spindle poles in endopolyploid tumor cells. .