Sclerostin Polyclonal Antibody

产品详情

产品名称

Sclerostin Polyclonal Antibody

产品货号

YM-A20340

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,ELISA,IHC

分子量

26kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from Sclerostin . at AA range: 130-210

特异性

Sclerostin Polyclonal Antibody detects endogenous levels of Sclerostin protein.

基因名称

SOST

蛋白名称

Sclerostin

别名

SOST;Sclerostin

基因ID-1

50964

SwissProt

Q9BQB4

背景

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq, Jul 2008],

细胞定位

Secreted, extracellular space, extracellular matrix .