Septin 5 Polyclonal Antibody

产品详情

产品名称

Septin 5 Polyclonal Antibody

产品货号

YM-A20365

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC

分子量

42kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from Septin 5 . at AA range: 180-260

特异性

Septin 5 Polyclonal Antibody detects endogenous levels of Septin 5 protein.

基因名称

SEPT5

蛋白名称

Septin-5

别名

SEPT5;PNUTL1;Septin-5;Cell division control-related protein 1;CDCrel-1;Peanut-like protein 1

基因ID-1

5413

SwissProt

Q99719

背景

septin 5(SEPT5) Homo sapiens This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq, Dec 2010],

细胞定位

Cytoplasm . Cytoplasm, cytoskeleton . In platelets, found in areas surrounding alpha-granules.