SF3b130 Polyclonal Antibody

产品详情

产品名称

SF3b130 Polyclonal Antibody

产品货号

YM-A20378

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA,IHC

分子量

140kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human SF3B3. AA range:231-280

特异性

SF3b130 Polyclonal Antibody detects endogenous levels of SF3b130 protein.

基因名称

SF3B3

蛋白名称

Splicing factor 3B subunit 3

别名

SF3B3;KIAA0017;SAP130;Splicing factor 3B subunit 3;Pre-mRNA-splicing factor SF3b 130 kDa subunit;SF3b130;STAF130;Spliceosome-associated protein 130;SAP 130

基因ID-1

23450

SwissProt

Q15393

背景

This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. [provided by RefSeq, Jul 2008],

细胞定位

Nucleus .