TAF II p135/p105 Polyclonal Antibody

产品详情

产品名称

TAF II p135/p105 Polyclonal Antibody

产品货号

YM-A20599

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IHC,IF,ELISA

分子量

110kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human TAF4. AA range:941-990

特异性

TAF II p135/p105 Polyclonal Antibody detects endogenous levels of TAF II p135/p105 protein.

基因名称

TAF4/TAF4B

蛋白名称

Transcription initiation factor TFIID subunit 4/Transcription initiation factor TFIID subunit 4B

别名

TAF4;TAF2C;TAF2C1;TAF4A;TAFII130;TAFII135;Transcription initiation factor TFIID subunit 4;RNA polymerase II TBP-associated factor subunit C;TBP-associated factor 4;Transcription initiation factor TFIID 130 kDa subunit;TAF;II;130;

基因ID-1

6874;6875

SwissProt

O00268;Q92750

背景

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that has been shown to potentiate transcriptional activation by retinoic acid, thyroid hormone and

细胞定位

Nucleus.