TESK1 Polyclonal Antibody

产品详情

产品名称

TESK1 Polyclonal Antibody

产品货号

YM-A20662

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,ELISA

分子量

68kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human TESK1. AA range:181-230

特异性

TESK1 Polyclonal Antibody detects endogenous levels of TESK1 protein.

基因名称

TESK1

蛋白名称

Dual specificity testis-specific protein kinase 1

别名

TESK1;Dual specificity testis-specific protein kinase 1;Testicular protein kinase 1

基因ID-1

7016

SwissProt

Q15569

背景

testis-specific kinase 1(TESK1) Homo sapiens This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases (LIMKs). The encoded protein can phosphorylate myelin basic protein and histone in vitro. The testicular germ cell-specific expression and developmental pattern of expression of the mouse gene suggests that this gene plays an important role at and after the meiotic phase of spermatogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015],

细胞定位

Cytoplasm . Cytoplasm, perinuclear region . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cell projection, lamellipodium . Colocalizes with SPRY4 in vesicular spots in the cytoplasm (PubMed:15584898). Localized to F-actin-rich lamellipodia at the cell periphery following fibronectin-mediated cell adhesion of Schwann cells (By similarity). .